الوظيفة البيولوجية لحمض الفورميك

Formic acid has important biological functions in livestock and poultry production, including acidification, sterilization, immune enhancement, and intestinal development.

  • Reduce the pH of the feed

With the increase of ammonium formate addition, the pH of the feed gradually decreased (JH Eisemann and E van Heugten, 2014).

(2) Reduce the pH of the chyme at the front of the digestive tract of animals

Formic acid has strong hydrogen supply capacity and low pKa value. Formic acid preparations can reduce the pH of the contents of the front end of the digestive tract. The intestinal tract has a strong buffering property, and livestock and poultry themselves have a mechanism for regulating intestinal pH, so the intestinal pH generally does not fluctuate in a large range.

(3) Improve digestive enzyme activity

The addition of formic acid preparations to the diet can significantly increase the activities of pepsin and amylase, and promote the digestion of vegetable protein and starch.

(4) Improve the digestion and utilization rate of nutrients by animals

The main mechanisms of formic acid preparations to improve the digestion and utilization of nutrients include: activating pepsinogen, providing a suitable pH environment for pepsin, denaturing plant protein and starch, and improving endogenous enzyme activity.

(5) Improve animal intestinal flora

Formic acid has a strong inhibitory effect on Escherichia coli, Salmonella, Staphylococcus aureus and other pathogens.

Antibiotics (AGP) resulted in a decrease in jejunal goblet cell density and a decrease in the ratio of Firmicutes to Bacteroidetes, suggesting that AGP may negatively affect gut immunity and microbiota homeostasis. Formic acid preparations can increase the ratio of Firmicutes to Bacteroidetes, which is beneficial to maintain intestinal microbial homeostasis.

(6) Promote the development of intestinal villi

Studies have shown that formic acid organic acid preparations can promote intestinal development, thereby improving the utilization of nutrients.

The application value of formic acid in feed is reflected in: strong bactericidal and bacteriostatic, maintain intestinal homeostasis, reduce diarrhea; efficiently provide H+ in the stomach, promote nutrient digestion, improve nutrient utilization; clean feed, keep fresh and prevent mildew; reduce Ammonia emissions; inhibit and kill pathogenic bacteria in drinking water and pens, and strengthen biological control systems for livestock and poultry.

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